The activity of five cephalosporins against Bacteroides fragilis.
نویسندگان
چکیده
Forty-two isolates of Bacteroides fragilis were tested against five new cephalosporin antibiotics by two quantitative methods, microdilution and agar dilution. Results indicated satisfactory methodological agreement. Mean minimum inhibitory concentrations (MIC) of thienamycin, moxalactam, and ceftizoxime were significantly lower than with the other antibiotics tested.
منابع مشابه
Cephalosporinase activity in Bacteroides fragilis.
Cephalosporinase activity was demonstrated in all of 10 strains of Bacteroides fragilis investigated. Low rates of hydrolysis of cephalosporins (0.25 to 3.5 mumol of cephaloridine per h per 10(9) cells) were found, but no activity against penicillin substrates was detected. In two strains the cephalosporinase activity was increased 40-and 80-fold by growing cells in the presence of penicillin. ...
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ورودعنوان ژورنال:
- Annals of clinical and laboratory science
دوره 12 1 شماره
صفحات -
تاریخ انتشار 1982